Takayuki Shindo Selected Research

Vascular System Injuries

6/2013	Endogenous CGRP protects against neointimal hyperplasia following wire-induced vascular injury.
11/2005	Synthetic retinoid Am80 suppresses smooth muscle phenotypic modulation and in-stent neointima formation by inhibiting KLF5.
1/2003	KLF5/BTEB2, a Krüppel-like zinc-finger type transcription factor, mediates both smooth muscle cell activation and cardiac hypertrophy.
8/2002	Resistance to neointimal hyperplasia and fatty streak formation in mice with adrenomedullin overexpression.

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Takayuki Shindo Research Topics

Disease

9	Fibrosis (Cirrhosis) 01/2023 - 01/2003
6	Neoplasms (Cancer) 05/2022 - 08/2004
6	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 08/2004
6	Infections 01/2016 - 04/2008
5	Heart Failure 07/2022 - 01/2010
5	Hypertrophy 01/2021 - 01/2003
5	Cardiomegaly (Heart Hypertrophy) 10/2019 - 01/2003
4	Ischemia 01/2019 - 08/2004
4	Vascular System Injuries 06/2013 - 08/2002
3	Macular Degeneration (Age-Related Maculopathy) 01/2023 - 06/2015
3	Inflammation (Inflammations) 01/2023 - 05/2017
3	Choroidal Neovascularization 01/2023 - 06/2015
3	Neoplasm Metastasis (Metastasis) 05/2022 - 01/2016
3	Atrophy 05/2020 - 10/2004
3	Alcoholic Fatty Liver 01/2020 - 09/2017
3	Liver Cirrhosis (Hepatic Cirrhosis) 01/2020 - 05/2009
3	Chronic Hepatitis (Chronic Active Hepatitis) 10/2019 - 05/2009
3	Hyperplasia 06/2013 - 08/2002
3	Body Weight (Weight, Body) 05/2006 - 05/2003
2	Aortic Dissection 04/2024 - 01/2022
2	Hypersensitivity (Allergy) 09/2022 - 10/2013
2	Obesity 11/2021 - 12/2018
2	Hemorrhage 01/2019 - 09/2011
2	Atherosclerosis 06/2013 - 05/2006
2	Hepatitis 05/2009 - 04/2006
2	Respiratory Hypersensitivity 06/2007 - 11/2002
2	Neointima 11/2005 - 01/2003
1	Heart Diseases (Heart Disease) 07/2022
1	Myocardial Infarction 07/2022
1	Neuralgia (Stump Neuralgia) 01/2022
1	Thoracic Aortic Aneurysm 01/2022
1	Hypertension (High Blood Pressure) 11/2021
1	Dyslipidemias (Dyslipidemia) 11/2021
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 11/2021
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2021
1	Papilledema 05/2020
1	Lymphedema (Milroy Disease) 12/2019
1	Nociceptive Pain 12/2019
1	Cachexia 10/2019
1	Chronic Disease (Chronic Diseases) 10/2019
1	Iron Overload 05/2019
1	Edema (Dropsy) 01/2019
1	Thrombosis (Thrombus) 01/2019
1	Retinal Vein Occlusion 01/2019

Drug/Important Bio-Agent (IBA)

17	AdrenomedullinIBA 01/2023 - 08/2002
10	Peptides (Polypeptides)IBA 01/2021 - 08/2004
7	Calcitonin Gene-Related PeptideIBA 01/2022 - 04/2006
5	Transcription Factors (Transcription Factor)IBA 01/2023 - 01/2003
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2011
5	Retinaldehyde (Retinal)IBA 05/2020 - 06/2013
4	Angiotensin IIIBA 01/2022 - 01/2003
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023 - 05/2017
3	Placental ExtractsIBA 01/2020 - 09/2017
3	Choline (Choline Chloride)IBA 01/2020 - 09/2017
3	tamibaroteneIBA 05/2006 - 01/2003
2	Lysine (L-Lysine)FDA Link 04/2024 - 01/2022
2	Receptor Activity-Modifying Protein 2IBA 01/2021 - 07/2015
2	Therapeutic UsesIBA 05/2020 - 05/2016
2	Fluorescein (Funduscein)FDA LinkGeneric 01/2019 - 06/2015
2	Peptide Hydrolases (Proteases)FDA Link 01/2016 - 01/2012
2	AcidsIBA 01/2016 - 05/2009
2	Protein Isoforms (Isoforms)IBA 01/2016 - 01/2012
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2016 - 06/2011
2	Factor V (Coagulation Factor V)IBA 01/2010 - 01/2005
2	Concanavalin AIBA 05/2009 - 04/2006
2	ApolipoproteinsIBA 05/2006 - 08/2002
2	RetinoidsIBA 05/2006 - 11/2005
2	Histamine (Histamine Dihydrochloride)FDA Link 10/2004 - 05/2003
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 01/2023
1	Durapatite (Hydroxylapatite)IBA 09/2022
1	titanium dioxide (Titania)FDA Link 09/2022
1	Adenosine Triphosphate (ATP)IBA 07/2022
1	Dynamins (Dynamin)IBA 07/2022
1	Myosin Heavy Chains (Myosin Heavy Chain)IBA 01/2022
1	IntegrinsIBA 01/2022
1	C-Reactive ProteinIBA 11/2021
1	Biomarkers (Surrogate Marker)IBA 11/2021
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2021
1	Retinal Pigments (Pigments, Visual)IBA 01/2021
1	Adrenomedullin ReceptorsIBA 01/2021
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2021
1	Hydroxyproline (4 Hydroxyproline)IBA 01/2021
1	Actins (F Actin)IBA 01/2021
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 01/2021
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021
1	CXC ChemokinesIBA 01/2021
1	Methionine (L-Methionine)FDA Link 01/2020
1	NeuropeptidesIBA 12/2019
1	IronIBA 05/2019
1	Rose BengalIBA 01/2019
1	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 01/2019
1	Coloring Agents (Dyes)IBA 01/2019
1	isothiocyanic acidIBA 01/2019

Therapy/Procedure

7	Lasers (Laser) 01/2023 - 08/2004
4	Therapeutics 01/2022 - 01/2012
2	Transplantation 05/2022 - 01/2016
1	Ligation 01/2022
1	Analgesia 01/2022
1	Intravitreal Injections 01/2021
1	Light Coagulation 01/2019